Last reviewed: May 12, 2026 Last updated: May 12, 2026

Written by: Jay Hastings , CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

The Impact of Age-related Macular Degeneration (AMD) on Vision Health

The debilitating eye condition known as Age-related macular degeneration (AMD) impacts a large number of people especially those who are older than 60 years. The progressive disease attacks the macula which serves as a vital segment of the retina that manages central vision. The primary cause of blindness in the elderly population requires researchers to understand AMD's genetic and environmental contributors to enable early detection and effective management. Genetic factors account for about 45-70% of the difference in people's vulnerability to AMD development. Although researchers have not yet determined the precise cause of AMD scientists recognize both genetic and environmental elements as contributing factors to its development. Researchers have found that age along with smoking habits and diet and genetic background combined with high blood pressure heart conditions and intense sun exposure serve as potential risk factors for AMD. AMD symptoms develop slowly and cause reading difficulties along with blurred vision and dark spots in the central field of vision. Prompt medical attention from an eye care professional is necessary when you recognize any of these symptoms for a complete examination. People who have a genetic predisposition to AMD should receive regular eye examinations following their 60th birthday. The medical community offers numerous treatments to decelerate AMD progression and protect vision despite the absence of a cure. The condition may be effectively managed through interventions such as anti-VEGF injections, laser therapy, and nutritional supplements. The risk of developing AMD can be considerably reduced and its progression slowed by making lifestyle changes to eat better and stop smoking. The management of this vision-threatening condition requires both understanding AMD’s genetic basis and recognizing how environmental factors influence its development. People who learn about AMD symptoms and risk factors along with treatment methods can protect their vision and maintain eye health through proactive actions. Use PlexusDx Precision Health & Wellness tests to obtain important information about your genetic risks and make educated choices regarding your eye health.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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