What is Nutrigenomics (NGx)?

Nutrigenomic (NGx) testing investigates the influence of genetic makeup on nutrient needs. The generic advice to “eat right and exercise” means different things depending on your genetics. This test can help you outline what changes you can make to your daily habits that can impact your weight, energy, and overall health.

Is Nutrigenomics (NGx) right for me?

Everyone can benefit from knowing how your genetics influence your body’s response to nutrition, providing you with a lifetime of guidance.

Does my doctor need to order these tests?

No. You can order the test directly.

Can I order these tests for someone else?

Yes. You can purchase a test for another person. They will need to activate their test kit on our website upon receipt. For minors, parental or guardian consent is required for activation. Once someone has successfully responded to PGx registration questions, PlexusDx's Clinician Network will order your test for you.

How long does it take to receive my results?

Once we receive your sample at the lab, it takes approximately 10-14 business days to complete the review and analysis for PGx tests and 2-4 weeks for NGx tests.

Can I use FSA/HSA to cover these tests?

Yes, the cost of each test is typically reimbursable through both Flexible Spending Accounts (FSA) and Health Savings Accounts (HSA).

What is Flex and what is their relationship with PlexusDx?

PlexusDx has partnered with Flex to allow you to use your Health Savings Account (HSA) or Flexible Spending Account (FSA). This means you can now use your HSA or FSA debit card to buy health and wellness tests with pre-tax dollars, resulting in net savings of 30-40%, depending on your tax bracket.

How do I pay with my HSA or FSA card?

To use your HSA or FSA debit card, add products to your cart as usual. At checkout, select "Flex | Pay with HSA/FSA" as your payment option, enter your HSA or FSA debit card, and complete your checkout as usual. If you don't see "Flex | Pay with HSA/FSA," you may be in Shop Pay. Select "checkout as guest" to view more payment options.

What if I don't have my HSA/FSA card available?

If you don't have your HSA or FSA card handy, still select "Flex | Pay with HSA/FSA" as your payment method. Enter your credit card information and Flex will email you an itemized receipt to submit for reimbursement.

Why can't I see Flex as a payment method?

The key here is to make sure you are logged out of Shop Pay. One of the easiest ways to do this is to go through checkout in an incognito window.

Why is my HSA/FSA card being declined?

HSA/FSA cards are debit cards, and the most common reason for declines is insufficient funds. Reach out to your HSA/FSA administrator to confirm your balance.

I submitted my Flex itemized receipt for reimbursement and my FSA requires more information.

Please forward us the request from your FSA, and we will work with the Flex team to issue you a new receipt.

Help! I didn't receive an email from Flex with my itemized receipt and/or letter of medical necessity. What should I do?

Please check your spam folder, as sometimes emails from notifications@withflex.com may be automatically filtered as spam by some email service providers. If you still can't find it, please email support@withflex.com and let them know the email address associated with your order.

I would like to use multiple HSA/FSA cards to pay for an item. Can I do that?

No, unfortunately, this isn't a supported feature right now. If there are insufficient funds in a single HSA or FSA account, you can instead enter a credit card on the Flex checkout page. You will receive an itemized receipt and/or Letter of Medical Necessity from Flex, which you can submit for reimbursement.

Is sales tax covered by HSA/FSA funds, or is it treated separately?

Sales tax for eligible items is also covered by HSA/FSA funds. If the customer has a split cart, the tax will be divided among the cards based on the items.

My HSA/FSA Claim was denied. What should I do?

We strongly recommend checking with your HSA/FSA provider to see if a purchase is eligible prior to completing the purchase. However, if you believe your claim has been wrongly denied, please send over any response from your HSA/FSA provider to us so we can share it with Flex and receive guidance on the next best steps to take. Please note that employer-sponsored FSAs can determine what products are eligible beyond the IRS's guidelines, so it's extremely important to check prior to purchase.

Can a customer purchase a product now and apply for FSA reimbursement in the next calendar year?

The ability to apply for FSA reimbursement in a future calendar year depends on the policy of the specific FSA provider. Most FSA administrators require that the purchase be made during the time of coverage. For example, if the FSA coverage is for 2025, all purchases typically need to be made and/or submitted for reimbursement within that coverage period. However, some administrators may have more flexible rules regarding the timing of when the expense occurred. We recommend that customers review their plan policy to confirm the details. Note: Health Savings Accounts (HSAs) are different and generally allow for reimbursement at any time, even in future years.

Can old (non-Flex) customers use their order confirmation email to apply for HSA/FSA reimbursement?

Unfortunately, for purchases made without using Flex in the checkout to receive an itemized receipt, it may be difficult to apply for reimbursement. For Health Savings Accounts (HSAs), consumers can use an itemized receipt for reimbursement anytime after they have made the purchase, even if it is many years later. For Flexible Spending Accounts (FSAs), most accounts require that the purchase was made in the calendar year during which the consumer had the FSA, as FSAs typically do not roll over. Some FSAs offer a buffer window, allowing customers additional time to submit receipts for expenses incurred during the previous calendar year.

Can I speak to a live person?

Customer Support is available 9am – 5pm EST Monday – Friday. 877-760-2333 support@tests.plexusdx.com

What is covered by the Precision Wellness Test reports?

The PlexusDx Precision Wellness Tests cover over 1000 genetic reports related to your overall health. Here is a small sample... How you process macronutrients: Dietary protein Dietary fats Carbohydrates Choosing the right types of dietary fat: Saturated fat Omega-3 Unsaturated fat Getting enough vitamins: Vitamin B6 Vitamin E Vitamin D Vitamin B12 Folate Vitamin B2 Vitamin C Vitamin A Vitamin K Getting enough minerals: Zinc Magnesium Iron Potassium Selenium Calcium Improving your eating habits: Tendency to overeat Sugar cravings Snacking

What steps should I take after getting my test results?

Receiving your results marks a significant moment in your health journey. They serve as an insightful tool in managing your healthcare effectively. Should you have any inquiries about your results or if you're interested in obtaining clinical advice, please don't hesitate to contact us at results@plexusdx.com . Additionally, every client who completes our tests has the opportunity to be connected with either a Clinical Pharmacist or Registered Dietitian through the PlexusDx Network upon request.

Does this test provide ancestry information?

This DNA test doesn't offer ancestry details. It focuses solely on how your genes affect your response to specific medications.

Can this test predict my disease risk?

This DNA test isn't designed to assess your likelihood of developing diseases, including cancer.

How does PlexusDx handle my DNA sample?

Your genetic data is utilized solely for report processing, with no storage or use beyond this requirement. Rest assured, we promptly discard your sample after processing is complete.

Will you share my data with my insurance or employer?

No. Your data is for you, and you only.

Methylation & Detox Genetic Test (Expanded Edition)

Methylation & Detox Genetic Test (Expanded Edition)

Name: Methylation & Detox Genetic Test (Expanded Edition)
Brand: PlexusDx
SKU: PlexusDx-Precision-Diabetes-Management-Genetic-Test
Price: 349.0 USD
Availability: InStock

$349.00

370+ DNA reports including MTHFR, COMT, BHMT, Weight Loss, Diet, Nutrition, and Folate Metabolism.

Unlock comprehensive insights with the Methylation & Detox Genetic Test (Expanded Edition), designed to uncover genetic factors affecting diet, weight loss, nutrition, detoxification and methylation—key to cognitive health, hormone balance, and overall well-being. Understand crucial genes like MTHFR and MTRR, receive tailored strategies for nutrient absorption and toxin clearance, and access personalized supplement plans and 10,000+ recipes for lasting health optimization.

Methylation & Detox Genetic Test (Expanded Edition)

$349.00

Use the Power of Genetics to Take Control of Your Methylation, Detox, and Nutrition

With countless wellness options, finding what truly works for your body can be overwhelming. Precision Wellness Tests provide a personalized roadmap by analyzing how your unique genetics impact key health areas. These insights empower you to make informed decisions aligned with your goals—because health isn’t just about the genetic cards you’re dealt; it’s how you play them.

370+ DNA reports including MTHFR, COMT, BHMT, Weight Loss, Diet, Nutrition, and Folate Metabolism

The Methylation & Detox (expanded edition) Genetic Test offers a personalized approach to managing your health by examining the unique genetic factors that influence your metabolism, methylation, and overall nutritional needs. This test combines insights into the genetics of diet and nutrition, providing tailored food recommendations that support overall wellness. By revealing genetic influences on metabolic health, it offers actionable advice to help maintain balance in weight and blood sugar control. Additionally, the test explores how your body processes and distributes weight and fat, with customized strategies for effective weight management. With specific insights into blood sugar regulation and metabolism, this expanded edition test delivers a comprehensive toolkit to support you in managing your health and maintaining a balanced, health-conscious lifestyle.

Your Methylation & Detoxification (expanded edition) Genetic Test comes with evidence-based, actionable, and personalized supplement and meal plan recommendations including over 10,000 recipes.

WHAT YOU GET: 370+ personalized genetic reports and recommendations related to Methylation, Detoxification, Glucose, Insulin, HbA1c, Vitamins, Minerals and much more

WHY PRECISION HEALTH? Precision Health tailors wellness solutions targeting areas like Weight Management, Diet, Methylation Pathways and more based on your unique DNA

HOW DOES IT WORK? Once you've opened your kit, register by following the instructions inside. Then, collect your sample and mail it back to us using the prepaid return mailer.

ACTIONABLE REPORTS: Practical reports for improving your overall wellness, including insights for Blood Sugar, Folate Cycle, Keto Diet, Supplements, Diet and Lifestyle Recommendations

TARGETED INSIGHTS: Tailor your diet, supplements, and lifestyle to your genetic makeup for optimal health and performance.

CUSTOM MEAL PLANS: Discover which foods and meal plans you should be eating based on your genetics. Identify optimal intake of macros, vitamins, and minerals. Includes over 10,000 recipes.

ADVANCED DNA TESTING: Get comprehensive reports with personalized diet, supplement, and lifestyle recommendations to achieve your health goals. Analysis of over 200 million genetic variants.

YOUR PRIVACY MATTERS: Your privacy is our priority. We use HIPAA compliant security and advanced encryption, ensuring your personal information is always protected.

Make Targeted Changes Based on Your DNA

With personalized dietary, supplement, and lifestyle suggestions, you will understand why specific health recommendations are right for your body and tailored to meet your current health needs. Our recommendations are crafted based on your genetic profile because there is no such thing as one-size-fits-all.

50 %

of adults in the U.S. have at least one chronic health condition, many of which are impacted by genetic factors.¹

80 %

of Americans have nutrient deficiencies, which can impact everything from cognitive function to immunity and metabolic health.²

25 %

of U.S. adults are affected by mental health conditions, where genetic predispositions play a key role in conditions such as anxiety, depression, and stress management.³