PlexusDx Upgrade and save
Rated Excellent on

Your new, lower price is ready. Keep your momentum, medication, progress and routine.

You asked for a lower price, and new pharmacy partners made it possible. One short intake form before your next refill moves your care to our new platform, at your new price.

Upgrade and save See your new price
Takes 1 to 3 minutes Your dose may need to go up. Your price won’t. HSA and FSA cards accepted Cancel in one click
Smiling woman holding a glass of water in a bright kitchen
Nothing starts over.
New price from
$99/mo
Semaglutide, 12-month plan
How to upgrade

Three steps. One to three minutes.

Everything is online. Upgrade before your next refill and your next refill comes on your new plan, with nothing starting over.

1

Fill out your new intake form

Choose your plan on the way. It’s the same kind of short questionnaire you’ve done before.

2

Snap a photo of your current medication

When the form asks, take a quick photo of the medication you have now so your provider can see where you are.

3

Your provider reviews and decides

A licensed provider in your state reads it all and decides your treatment. Then your medication ships free, as it does today.

Upgrade and saveAlready upgraded? Thank you. There’s nothing else to do.
New pricing

What you pay now, and what you’ll pay.

Prices are per month for the plan length shown. Every plan is all-inclusive, with no teaser rates or hidden fees. Pick your plan below and carry on.

Per month · now to new
Your dose may need to go up. Your price won’t.
PlanSemaglutide injectionTirzepatide injection
1 month$189 now $149$289 now $189
3 months$169 now $129$269 now $169
6 months$149 now $109$249 now $149
12 monthsNew$99New$129
Medication
Plan length
{{selName}}
All-inclusive

{{wasLine}}

{{srSummary}}
{{saveText}}
Upgrade and save
KlarnaAffirmPay over time, or use your HSA/FSA card.

Prices are per month for the plan length shown. Longer plans are paid up front, or split with Klarna or Affirm. You’re charged $0 unless your provider approves your medication. A prescription is required, and a licensed provider decides your treatment.

Monthly price by plan length
Included with every plan
  • Prescription & provider visits
  • Syringes & supplies
  • Free shipping
  • 1:1 pharmacist support
  • Message your care team
  • Cancel in one click
Flexible payments

Pay over time, or use your HSA or FSA.

Split your plan into installments with Klarna or Affirm at checkout, or pay with your HSA or FSA card. Every payment is securely processed by Stripe.

Klarna
Affirm
FSA
HSA
Powered by Stripe

Installment plans through Klarna or Affirm are subject to an eligibility check and the provider's terms. HSA/FSA eligibility depends on your plan administrator.

Your care team

A medical team that’s yours.

When you upgrade, your care moves to a new medical team: Lone Star Virtual Health, PLLC, an independent practice of licensed providers.

  • No AI prescriptions. A licensed provider in your state reads your intake and decides your care.

  • Your provider, by name. You’ll always know who is treating you.

  • Care, not sales. Your provider’s pay does not depend on whether they prescribe or how much you spend.

PlexusDx is not the medical practice. Lone Star’s licensed team gives you your care.

A Lone Star Virtual Health provider
A Lone Star Virtual Health provider in scrubs
Lone Star Virtual Health, PLLCLicensed providers · Independent medical practice
Your new portal

More control over your care.

Your new portal puts you in charge: messages, refill timing, new requests and cancellation, all in one place.

Stay in touch

Message your care team

Your provider and our team, any time, just like now.

Your schedule

Refills that fit your life

Get a refill sooner before a vacation, or ship it to where you’ll be.

More options

Add another medicine

Just ask. Your provider checks every request.

Easy cancel

Cancel in one click

If your plans change, it’s simple.

Patient reviews

Five stars, in their own words.

Showing selected 5-star reviews, quoted word for word from our Trustpilot profile. Reviewer names withheld for privacy. Individual experiences vary; see important safety information.

BUILT INTO YOUR PLAN

You don’t have to
figure this out alone.

A Doctor of Pharmacy to talk to, whenever you have a question about your GLP-1.

UNLIMITED ACCESS

Your questions.
A real conversation.

Whether you have questions about side effects, drug interactions, or supplements, just book time for a one-on-one consultation with our GLP-1-experienced Doctor of Pharmacy.

After provider approval.
No extra consultation fee.
Jayden Lee, PharmD
Jayden Lee, PharmDPlexusDx
Medical Director

GLP-1-experienced Doctor of Pharmacy

Your questions are welcome here.

{{pcu.detail}}

Upgrade and save

$0 unless your provider approves medication.

Licensed online providersLicensed 503A pharmaciesLower prices, same medications
FAQ

Questions, answered.

Still have one? Reply to your upgrade email, or write to support@plexusdx.com.

Your care is moving to a new telehealth platform and a new medical team, Lone Star Virtual Health, PLLC. A licensed provider there needs their own intake, including a photo of your current medication, before they can prescribe. It takes 1 to 3 minutes.

Your provider reviews your intake and your current medication and decides your treatment. If your dose needs to go up, your price stays the same.

Before your next refill. Upgrade before it’s due and your next refill comes on your new plan, with nothing starting over. If your refill date has already passed, upgrade today and your provider will pick things up from there.

No. There is no upgrade fee. You’re charged $0 unless your provider approves your medication, and then only your new, lower price.

Yes. HSA and FSA cards are accepted. Longer plans are paid up front, or split into installments with Klarna or Affirm at checkout.

An independent medical practice of licensed providers. A provider licensed in your state reads your intake and decides your care, you’ll always know who is treating you, and your provider’s pay does not depend on whether they prescribe or how much you spend. PlexusDx is not the medical practice.

Message your provider and our team any time, get a refill sooner before a trip or ship it to where you’ll be, ask about adding another medicine, and cancel in one click if your plans change.

Once your provider approves you on the new platform, your refills come through it at your new price. If you have a question about your current plan, reply to your upgrade email or write to support@plexusdx.com.

No. Thank you. You can ignore the upgrade emails. If you’re not sure whether your upgrade went through, reply to the email or write to support@plexusdx.com.

Why patients trust us

Rated, verified and recognized.

Verify Approval for www.plexusdx.com

LegitScript certified. Independently reviewed against standards for licensing, privacy, valid prescriptions and advertising.

Verify our status
No. 31

Inc. Magazine named PlexusDx one of the 2026 fastest-growing private companies in the Southeast.

See the list

Keep your momentum.

Lower price, same medication, and nothing starts over. Upgrade in 1 to 3 minutes, before your next refill.

Woman walking along a coastal path at sunrise

Important safety information

Compounded semaglutide and tirzepatide are prescription medications. They are not FDA-approved, and the FDA does not review compounded medications for safety, effectiveness or quality.

Possible risk of thyroid tumors, including cancer. In studies with rodents, semaglutide and tirzepatide caused thyroid C-cell tumors. It is not known whether they cause these tumors, including medullary thyroid carcinoma (MTC), in people. Do not use them if you or a family member has ever had MTC, or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Tell your provider right away if you get a lump or swelling in your neck, trouble swallowing, hoarseness or shortness of breath.

Do not use these medications if you have had a serious allergic reaction to them. Tell your provider if you are pregnant, planning to become pregnant or breastfeeding, and before any surgery or procedure that uses anesthesia or deep sedation. Tirzepatide may make birth control pills less effective.

Serious side effects may include inflammation of the pancreas (pancreatitis), gallbladder problems, low blood sugar (especially with insulin or a sulfonylurea), kidney problems, severe stomach problems, serious allergic reactions, vision changes in people with type 2 diabetes, and, with semaglutide, increased heart rate. Stop using the medication and get medical help right away if you have severe stomach pain that will not go away.

The most common side effects include nausea, diarrhea, vomiting, constipation, stomach pain, tiredness, belching and heartburn. This is not a complete list. Talk to your provider about your full medical history and every medication you take.

PlexusDx

$99/mo is the monthly price of a 12-month semaglutide plan. Prices shown are per month for each plan length; longer plans are paid up front, or split with Klarna or Affirm. “Now” prices are the previous PlexusDx prices for the same plan; your current price may differ. Prescription required; a licensed provider decides your treatment. Individual results vary. Trustpilot rating as of September 29, 2026.

© 2026 PlexusDx

Upgrade and save · from $99/mo
Verify Approval for www.plexusdx.com

PlexusDx is LegitScript certified.

LegitScript is an independent group that reviews health companies. Tap the seal to check our status yourself.